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For genomics labs, diagnostics, and healthcare teams

NonStop Engineers the Software Behind Genomics and Healthcare

Platform, data, and bioinformatics engineering, accelerated by applied AI, built for diagnostic labs, precision medicine, and healthcare teams that need it to hold up in clinical production.

Book a 45-Minute Architecture ReviewSee What We Build

NonStop Shortens Turnaround From Order to Signed ReportSmartReq, StrixFlow, Varion, and ReportStudio are production-tested solutions for intake, pipeline monitoring, variant interpretation, and reporting, customized to your lab and owned by you.

ACMG / AMPFHIR R4NextflowGATKWGSHIPAASOC 2GDPRSnowflakeDatabricks
Three laboratory scientists in lab coats and safety glasses reviewing results at a microscope and laptop

In production

Proven in Regulated US Diagnostics and Healthcare Environments

0+Clients served
0+Team
0Founded
HIPAASOC 2GDPRCompliance ready

Trusted by Leading Diagnostics and Healthcare Organizations

  • AASM
  • BioMedict
  • BreathAI
  • ElderEase
  • Equipo
  • Headversity
  • HealthHelp
  • HumanFactorAnalysis
  • Kairos
  • Milligram
  • SmartRX
  • WeCare
  • Welltrinsic
  • WellVibe

Who we build for

Industries and Teams We Build For

NonStop builds the software for the people who run diagnostics and healthcare platforms, so they stay on the science and the care.

Clinical Diagnostics Labs

Clinical Diagnostics Labs

Bioinformatics, lab scientists, computational and infrastructure teams, clinical interpretation and genetics.

LIS and LIMS integration, custom LIMS development, lab workflow automation, and clinical reporting for CLIA-certified labs.

Diagnostic lab software development
Precision Medicine & Life Sciences

Precision Medicine & Life Sciences

Heads of Data Science, Bioinformatics Directors, and Clinical Lab Directors.

Bioinformatics pipelines, clinical diagnostics platforms, and AI-assisted variant interpretation.

Diagnostics and life sciences engineering
Healthcare & Digital Health

Healthcare & Digital Health

CTOs, CIOs, and CPOs at care delivery organizations, payers, and wearables companies.

EHR integration, HL7 and FHIR interoperability, and HIPAA-ready digital health platforms.

Healthcare software engineering
Health TechDiagnostic LabsLife Sciences

Forward Deployed Engineers

We Embed. You Innovate. We Deliver Impact.

Engineers who plug into your team and turn complex healthcare and diagnostics challenges into real-world results.

Move faster to productionSecure. Compliant. Scalable.Built for clinical impactWork as one team
Diagnostics Solutions
EHR & FHIR Integrations
AI & Workflow Automation
Cloud & Data Platforms
Lab Systems & LIMS
Forward Deployed Engineers
Talk to our forward deployed engineersHow embedded engineering works

The challenges we solve

The problems diagnostics, life science, and healthcare teams bring to NonStop most

And how the team engineers around them.

Pipelines That Break in Clinical Production

We build production-grade WES, WGS, RNA Seq, and gene panel workflows with versioning and reproducibility built in, so they hold up at the clinical scale and through audit.

Variant Interpretation Can't Keep Pace

We build AI that speeds tertiary analysis by filtering and pre-classifying variants, prioritising VUS, and aggregating evidence, with ACMG/AMP classification, so bioinformaticians stay focused on the call.

Research and omic data you can't turn into anything predictive

We build the full ML lifecycle on your proprietary datasets, from raw omic and experimental data through to governed, production-grade models you own.

Diagnostic & Clinical Data Scattered and Not Analysis-Ready

We build governed data lakes on Snowflake and Databricks, with quality, lineage, and PHI governance across instruments, LIMS, and EHRs.

Systems That Don't Talk to Each Other

We connect your platforms, EHRs like Epic and Cerner, LIMS, and instruments through HL7 v2, FHIR R4, and Mirth Connect, so data moves as one traceable workflow.

Software That Won't Survive a CLIA, CAP, or HIPAA Audit

We engineer audit trails, access controls, and human-in-the-loop review into every system, so the lab walks into an inspection ready. Certification stays with the lab.

Book A Consultation

Our expertise

Platform, Data, and Bioinformatics Engineering, Accelerated by Applied AI

NonStop is a healthcare and life sciences software company delivering platform engineering, data engineering, and bioinformatics engineering, accelerated by applied AI. Every system is built for the compliance and scale that regulated labs and healthcare organizations work under. Tap a petal to explore.

Engineers reviewing a platform dashboard together

Platform Engineering

Portals, interoperability and workflow software designed for high concurrency and real clinical use.

Patient & Provider Web PortalsCustomer-experience web portals and mobile apps for patients and providers.
Medical Data InteroperabilityEHR and LIMS integration across Epic, Cerner, HL7 v2, FHIR R4, Mirth Connect, and SMART on FHIR.
Revenue Cycle ManagementRCM and payer-workflow automation that reduces billing errors and speeds reimbursement.
Clinical Decision Support SystemsSoftware that brings the right data to the point of care, built to survive regulation and scale.
Talk to Our Platform Engineering Experts
Analyst working through data tables and charts

Data Engineering

Governed lakes and pipelines so diagnostic and clinical data is analysis-ready.

Governed Data Lakes & WarehousesSnowflake and Databricks, with quality, lineage, and PHI governance.
Data Quality & GovernanceComprehensive governance for PHI and diagnostic data, aligned to HIPAA.
Streaming & Batch ProcessingAirflow, dbt, Spark, and Athena pipelines sized for diagnostic and clinical volumes.
Data HarmonizationOne analytical source of truth across instruments, LIMS, and EHRs.
Talk to Our Data Engineering Experts
Scientist working with genomic data in a lab

Bioinformatics Engineering

Clinical-grade pipelines, monitoring and interpretation systems.

Pipeline Development at ScaleWES, WGS, RNA-Seq, and gene panels with Nextflow, WDL, Snakemake, and GATK.
Pipeline Monitoring & ObservabilityFailure detection and cost-per-sample visibility built into every workflow.
ACMG/AMP Variant AnalysisClassification aligned to ACMG/AMP with traceability for clinical and audit use.
Variant Knowledge Base SystemsKMS platforms that preserve a lab's interpretation history.
Talk to Our Bioinformatics Engineering Experts
Two engineers discussing AI model output

Applied AI

AI should respect the domain, and the system around it should survive real-world use.

AI-Accelerated DeliveryAI coding assistants such as Claude and Codex, with senior engineers reviewing what ships.
Domain-Specific Model Fine-TuningVariant interpretation, VUS prioritisation, and predictive lab analytics on your data.
Agentic Frameworks & RAGRAG over verified clinical and diagnostic data, plus AI document extraction.
AI PhilosophyNarrow, deliberate, and tied to real workflows.
Talk to Our Applied AI Experts

How we work

AI should respect the domain

…and the system around it should be strong enough to survive real-world use. The problems we care about sit at the intersection of three things:

  • Deep domain understanding in diagnostics and healthcare
  • Applied AI that is narrow, deliberate, and tied to real workflows
  • Strong engineering that can survive regulation, scale, and production reality
NonStop sits where deep domain focus, applied AI and strong engineering discipline meet

Diagnostics software solutions

Diagnostics Software Solutions Your Lab Can Run From Day One

Six ready-to-use, customizable solutions that each fix a specific slowdown in your lab, from requisition intake to the signed report.

SmartReq

Turns patient requisition intake into clean, structured orders with AI-powered form extraction, cutting billing errors from manual entry.

Learn more → about SmartReq
Book a 15-Minute Scoping Call

The production stack

The Production Stack Behind Everything We Build

Established, widely-used tools your engineers already work with, chosen to run reliably as your volume grows. Hover or tap a logo.

Pipelines

  • NextflowNextflow
  • WDLWDL
  • GATKGATK
  • DockerDocker
  • ApptainerApptainer

Nextflow · WDL · GATK · Docker · Apptainer

Cloud & Infra

  • GCPGCP
  • AzureAzure
  • KubernetesKubernetes
  • TerraformTerraform
  • AWSAWS

GCP · Azure · Kubernetes · Terraform · AWS

Data & Analytics

  • SnowflakeSnowflake
  • DatabricksDatabricks
  • Amazon AthenaAmazon Athena
  • Apache SparkApache Spark
  • AirflowAirflow
  • dbtdbt

Snowflake · Databricks · Amazon Athena · Apache Spark · Airflow · dbt

Interoperability

  • InteroperabilityInteroperability
  • FHIR R4FHIR R4
  • Mirth ConnectMirth Connect
  • EpicEpic
  • CernerCerner

Interoperability · FHIR R4 · Mirth Connect · Epic · Cerner

Application Stack

  • JavaJava
  • Dot NetDot Net
  • ReactReact
  • AngularAngular

Java · Dot Net · React · Angular

Why teams choose NonStop

Why Diagnostics and Healthcare Teams Choose NonStop

Most teams weigh three risky options: a dev shop that doesn't know the science, a platform they rent but never own, or a year spent hiring in-house. NonStop is the fourth option.

A diagnostics-native team, not generalists who pivoted

Bioinformatics engineers and life-science PhDs alongside platform, data, and cloud engineers, already fluent in ACMG/AMP, Nextflow, GATK, FHIR, and HL7.

A decade of delivery in regulated production

90+ organizations across 6+ countries since 2015, in HIPAA, SOC 2, and GDPR environments.

Diagnostics solutions already built across the lab workflow

SmartReq, Intergenix, StrixFlow, Varion, GENVAR, and ReportStudio: production-tested from requisition intake to signed report.

One accountable team, all the way to clinical production

Forward-deployed engineers build platform, data, and bioinformatics as one system and stay until it runs reliably at clinical volume, closing the gap where most projects stall between demo and integration.

The science stays in charge

AI for variant interpretation, VUS prioritisation, and lab analytics with human-in-the-loop review, so the scientist keeps the final call.

The right compliance posture, and the IP stays yours

Engineered for HIPAA, SOC 2, GDPR, and the CLIA and CAP environment. No software is compliant on its own, so certification stays with your lab, and the IP stays with you.

On-site and embedded engineering deployment for US-based clients

When required, we deploy engineers on-site, capable of resolving on-site challenges directly.

Case studies

Case Studies

Platform modernization

A Genetic Testing Lab Modernized Its Core Platform Without Stopping Operations

NonStop rebuilt a genetic testing lab’s order, reporting, and billing platform off a decade-old monolith, one surface at a time, while the lab kept processing clinical orders. No downtime, no big-bang cutover.

20msOrder search across 70,000 records went from seconds to about 20 milliseconds
Weeks → DaysNew hospital onboarding dropped from weeks to days
2× fasterFeature delivery speed roughly doubled, with zero disruption
Read the full case study →

Pipeline monitoring

Full Visibility Into the Bioinformatics Black Box

NonStop built a workflow-agnostic monitoring platform that connected a diagnostics lab’s LIMS directly to pipeline results, with real-time alerting and per-sample status across every pipeline.

4–6 hrsBioinformatics turnaround dropped from 12–24 hours, on the same compute
Hours → SecsFailure detection went from hours to seconds
AutoPer-sample cost attribution and an automatic CAP/CLIA audit trail
Read the full case study →

AI intake

AI-Powered Intake That Reads Every Requisition Form

NonStop built an on-premise AI extraction system that reads each requisition form, identifies the provider template, extracts every field, and validates it against the lab schema before anything reaches the LIS.

Every → ExceptionsManual touch dropped from every form to exceptions only
20+ templatesHandled automatically, a new provider is a template, not a retraining cycle
HIPAA cleanPatient data never leaves the lab, processed on-premise
Read the full case study →

Reporting platform

A Reporting Platform That Put Lab Teams Back in Control

NonStop replaced a hardcoded, developer-dependent reporting system with a role-separated report builder, template versioning, and an automated sign-off engine.

3–4 mo → 1–2 wksNew report types, owned by the lab team
Sprints → HoursRoutine reporting changes moved from engineering sprints to hours
Full historyTemplate version history gives clean rollback for CAP, CLIA, and ISO 15189 audits
Read the full case study →
See all case studies

Hear From Our Client

They didn't just build. They helped us sell.

JLDr. Joseph A. LeutzingerFounder, HIS

Read client reviews

Insights

Insights for Diagnostics and Healthcare Teams

Blogs, Diagnostics

WET Lab and Bioinformatics Integration for NGS Labs

Posted by MahendraContinue reading →
Blogs, Diagnostics

In-House vs. Outsourced Bioinformatics Engineering

Posted by MahendraContinue reading →
Blogs, Diagnostics

How to Build a Traceable Diagnostics Laboratory Workflow

Posted by MahendraContinue reading →
Read the blog

Centers of excellence

Built to De-Risk Digital Transformation

NonStop’s Centers of Excellence (CoEs) enable enterprises to turn complex ideas into secure, scalable, production-ready digital platforms, without compromising compliance, performance, or speed. Each CoE operates as an integrated product engine, uniting domain specialists, product strategy, engineering, cloud, AI, and QA across the full lifecycle. For CIOs, CTOs, and product leaders, our CoEs provide clarity over chaos, protecting investment and enabling platforms that scale predictably.

One product engine

Applied AI

UI/UX

Frontend Development

Backend Development

Mobile App Development

QA Testing

CI/CD & Infrastructure Automation

Cloud Security & Audit

Data Engineering Services

Bioinformatics

Talk to Engineers Who Know Genomics and Healthcare

Book a 45-Minute Architecture Review

No pitch, just an honest read on whether to build, buy, or modernise, from a team that has built clinical genomics and healthcare software before.

Book a 45-Minute Architecture ReviewTake the AI readiness diagnostic