Proven in Regulated
US Genomics and Healthcare Environments
Industries and Teams
We Build For
NonStop builds the software for the people who run genomics and healthcare platforms,
so they stay on the science and the care.
Genomics & Clinical
Diagnostics Labs
Bioinformatics, lab scientists, computational and infrastructure teams, clinical interpretation and genetics.
Precision Medicine &
Life Sciences
Heads of Data Science, Bioinformatics Directors, and Clinical Lab Directors.
Healthcare &
Digital Health
CTOs, CIOs, and CPOs at care delivery organizations, payers,
and wearables companies.
The Challenges We Solve
The problems genomics, life science, and healthcare teams bring to NonStop most,
and how the team engineers around them.
Platform, Data, and Bioinformatics Engineering,
Accelerated by Applied AI
NonStop is a healthcare and life sciences software company delivering platform engineering, data engineering, and bioinformatics engineering, accelerated
by applied AI, for diagnostic labs, precision medicine companies, and healthcare organizations.
Every system is built for the compliance and scale that regulated labs and healthcare organizations work under.
Patient & Provider Web Portals
Customer-experience web portals and mobile apps for patients and providers, designed for high concurrency and real clinical use.
Medical Data Interoperability
EHR and LIMS modernization and integration across Epic, Cerner, HL7 v2, FHIR R4, Mirth Connect, and SMART on FHIR.
Revenue Cycle Management
RCM and payer-workflow automation that reduces billing errors and accelerates reimbursement cycles.
Clinical Decision Support Systems
Software that brings the right data to the point of care, built to survive regulation and scale.
Governed Data Lakes & Warehouses
Data warehouses and governed data lakes on Snowflake and Databricks, with quality, lineage, and PHI governance.
Data Quality & Governance
Comprehensive governance for PHI and genomic data, ensuring compliance with HIPAA and regulatory requirements.
Streaming & Batch Processing
Data processing pipelines with Airflow, dbt, Spark, and Athena, optimized for genomic and clinical data volumes.
Data Harmonization
Data transformation and harmonization across instruments, LIMS, and EHRs, creating a single source of analytical truth.
Pipeline Development at Scale
WES, WGS, RNA-Seq, and gene panels with Nextflow, WDL, Snakemake, and GATK — built for clinical production.
Pipeline Monitoring & Observability
Failure detection and cost-per-sample visibility built into every workflow, so issues are caught at the source.
ACMG/AMP Variant Analysis
Variant analysis and classification aligned to ACMG/AMP guidelines, with traceability for clinical and audit use.
Variant Knowledge Base Systems
KMS platforms that preserve a lab's interpretation history against analyst turnover and vendor lock-in.
AI-Accelerated Delivery
Accelerated delivery using AI coding assistants such as Claude and Codex, with senior engineers reviewing what ships.
Domain-Specific Model Fine-Tuning
AI-assisted variant interpretation, VUS prioritisation, and predictive lab analytics built on your proprietary data.
Agentic Frameworks & RAG
RAG over verified clinical and genomic data and AI document extraction for requisitions and EHR orders.
AI Philosophy
AI should respect the domain, and the system around it should be strong enough to survive real-world use. Narrow, deliberate, and tied to real workflows.
AI should respect the domain, and the system around it should be strong enough to survive real‑world use.
The problems we care about sit at the intersection of three things:
- Deep domain understanding in genomics, diagnostics, and healthcare
- Applied AI that is narrow, deliberate, and tied to real workflows
- Strong engineering that can survive regulation, scale, and production reality
Genomics Software Solutions Your Lab Can Run From Day One
Six ready-to-use, customizable solutions that each fix a specific slowdown in your lab, from requisition intake to the signed report.
The Production Stack Behind Everything We Build
Established, widely-used tools your engineers already work with, chosen to run reliably as your volume grows.
Why Genomics and Healthcare Teams Choose NonStop
Most teams weigh three risky options: a dev shop that doesn't know the science, a platform they rent but never own, or a year spent hiring in-house. NonStop is the fourth option.
Bioinformatics engineers and life-science PhDs alongside platform, data, and cloud engineers, already fluent in ACMG/AMP, Nextflow, GATK, FHIR, and HL7.
90+ organizations across 25+ countries since 2015, in HIPAA, SOC 2, and GDPR environments.
SmartReq, Intergenix, StrixFlow, Varion, GENVAR, and ReportStudio: production-tested from requisition intake to signed report.
Forward-deployed engineers build platform, data, and bioinformatics as one system and stay until it runs reliably at clinical volume, closing the gap where most projects stall between demo and integration.
AI for variant interpretation, VUS prioritisation, and lab analytics with human-in-the-loop review, so the scientist keeps the final call.
Engineered for HIPAA, SOC 2, GDPR, and the CLIA and CAP environment. No software is compliant on its own, so certification stays with your lab, and the IP stays with you.
Case Studies
Centers of Excellence
Built to De-Risk Digital Transformation
NonStop’s Centers of Excellence (CoEs) enable enterprises to turn complex ideas into secure, scalable, production-ready digital platforms, without compromising compliance, performance, or speed.
Each CoE operates as an integrated product engine, uniting domain specialists, product strategy, engineering, cloud, AI, and QA across the full lifecycle. This model reduces execution risk, accelerates delivery, and ensures audit-ready product aligned with compliance.
For CIOs, CTOs, and product leaders, our CoEs provide clarity over chaos, protecting investment, aligning innovation with measurable outcomes, and enabling platforms that scale predictably.
Book a 45-Minute Architecture Review
No pitch, just an honest read on whether to build, buy, or modernise, from a team that has built clinical genomics and healthcare software before. Software engineers, bioinformatics engineers, and post-graduates and PhDs in life science and biotechnology.